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We accept FL Medicare, FL Medicaid, Aetna First Health, and Cigna. For out-of-network insurance, a $200 flat rate applies
Introdcution to Whole Genome Sequencing
Introdcution to Whole Genome Sequencing
At MD Genetic Clinic, we specialize in Whole Genome Sequencing (WGS), the most comprehensive genetic test available today.
Unlike standard genetic panels, WGS examines nearly all of your DNA to look for changes that may explain your medical condition, reveal inherited risks, and guide personalized care.
At MD Genetic Clinic, we specialize in Whole Genome Sequencing (WGS), the most comprehensive genetic test available today.
Unlike standard genetic panels, WGS examines nearly all of your DNA to look for changes that may explain your medical condition, reveal inherited risks, and guide personalized care.
WGS can benefit:
WGS can benefit:
- Patients with complex or unexplained medical symptoms
- Families seeking answers for rare diseases
- Individuals who want to understand their genetic health risks
What can Whole Genome Sequencing Reveal ?
What can Whole Genome Sequencing Reveal ?
Positive Result
Positive Result
A change in your DNA is found that is very likely to explain your symptoms. This result can help confirm a diagnosis, guide treatment, and allow family members to be tested for the same genetic change.
A change in your DNA is found that is very likely to explain your symptoms. This result can help confirm a diagnosis, guide treatment, and allow family members to be tested for the same genetic change.
Negative Result
Negative Result
No genetic changes are found to explain your symptoms. This does not rule out a genetic condition, but may indicate that the cause is currently undetectable with existing technology.
No genetic changes are found to explain your symptoms. This does not rule out a genetic condition, but may indicate that the cause is currently undetectable with existing technology.
Variant of Uncertain Significance (VUS)
Variant of Uncertain Significance (VUS)
A change is found, but we do not yet know if it causes disease. Additional family testing or research may help clarify its meaning.
A change is found, but we do not yet know if it causes disease. Additional family testing or research may help clarify its meaning.
Incidental or Secondary Findings
Incidental or Secondary Findings
Sometimes, WGS reveals important health risks unrelated to your primary reason for testing.
The American College of Medical Genetics and Genomics (ACMG) recommends reporting certain “medically actionable” findings that could impact your future health.
Sometimes, WGS reveals important health risks unrelated to your primary reason for testing.
The American College of Medical Genetics and Genomics (ACMG) recommends reporting certain “medically actionable” findings that could impact your future health.
Trio and Duo Testing for Greater Accuracy
Trio and Duo Testing for Greater Accuracy
In many cases, testing both parents (trio) or one parent (duo) along with the patient helps clarify results.
Family participation can:
In many cases, testing both parents (trio) or one parent (duo) along with the patient helps clarify results.
Family participation can:
- Distinguish between inherited and new genetic changes
- Reduce uncertainty in results
- Improve overall accuracy
Risks & Limitations of Whole Genome Sequencing
Risks & Limitations of Whole Genome Sequencing
While WGS is powerful, it has important considerations:
While WGS is powerful, it has important considerations:
- Some genetic changes may be missed due to current technology limitations.
- Testing may uncover unexpected family relationships (non-paternity, consanguinity).
- Technical or labeling errors, while rare, can occur.
- Results may reveal risks for conditions unrelated to your current symptoms.
- Your results may evolve over time as scientific knowledge grows.
Your Informed Consent at MD Genetic Clinic
Your Informed Consent at MD Genetic Clinic
Purpose of the Consent Form
Purpose of the Consent Form
Before testing, we provide an Informed Consent document that explains:
Before testing, we provide an Informed Consent document that explains:
- Why the test is being ordered
- The possible outcomes (positive, negative, uncertain, secondary findings)
- How your sample will be used
- Your choices regarding data sharing and research participation
Your Choices
Your Choices
You will have the option to:
You will have the option to:
- Opt-in or out of receiving ACMG secondary findings
- Decide if your sample can be used for research or test improvement
- Control how your health data is shared
Confidentiality
Confidentiality
Your genetic information is protected by federal privacy laws. Results are only shared with your care team and anyone you authorize.
Your genetic information is protected by federal privacy laws. Results are only shared with your care team and anyone you authorize.
Download Full Consent Form (PDF)
Download Full Consent Form (PDF)
What to Expect Before, During, and After Whole Genome Testing
What to Expect Before, During, and After Whole Genome Testing
Pre-test genetic counseling to review your personal and family history
Pre-test genetic counseling to review your personal and family history
Sample collection (blood or saliva)
Sample collection (blood or saliva)
Trio/Duo participation if applicable
Trio/Duo participation if applicable
Result turnaround typically within 6–12 weeks
Result turnaround typically within 6–12 weeks
Post-test genetic counseling to review findings, next steps, and recommendations
Post-test genetic counseling to review findings, next steps, and recommendations
Why Choose MD Genetic Clinic for Whole Genome Sequencing
Why Choose MD Genetic Clinic for Whole Genome Sequencing
Led by a board-certified physician specializing in Medical and Biochemical Genetics
Led by a board-certified physician specializing in Medical and Biochemical Genetics
Expertise in diagnosing and managing rare and complex genetic conditions
Expertise in diagnosing and managing rare and complex genetic conditions
Convenient telehealth access
Convenient telehealth access
Guidance with insurance coverage and clear, transparent cost information
Guidance with insurance coverage and clear, transparent cost information
Schedule Your Whole Genome Sequencing Appointment
Schedule Your Whole Genome Sequencing Appointment
Take the first step toward answers.
Our genetic team will guide you through every stage, from counseling to results.
Take the first step toward answers.
Our genetic team will guide you through every stage, from counseling to results.
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