Arrhythmia & Cardiomyopathy Genetic    

Understanding Arrhythmia and Cardiomyopathy Genetic

Arrhythmias (abnormal heart rhythms) and cardiomyopathies (diseases of the heart muscle) can often have a genetic basis. Identifying the underlying genetic cause helps clarify the diagnosis, inform treatment, and guide lifestyle recommendations to reduce risks such as sudden cardiac arrest.

At MD Genetic Clinic, we aim to  identifying the underlying genetic cause. We can also recognize family members who may be at risk and ensure early monitoring, intervention, and personalized care.

Genetic Testing for Arrhythmias and Cardiomyopathies at MD Genetic

The genetic panel we offer provides a comprehensive analysis of the genes associated with inherited arrhythmias and cardiomyopathies. Because many of these conditions overlap clinically, broad panel testing allows for efficient evaluation based on a single indication.

Testing may be recommended for:

• Individuals with symptoms of an inherited arrhythmia or cardiomyopathy

• Family members of an individual with a known pathogenic variant

• Relatives of individuals who experienced sudden unexplained cardiac events

A genetic diagnosis can guide:

• Clinical monitoring and surveillance

• Medication and activity recommendations

• Screening of at-risk relatives

Conditions Tested Include:

• Andersen-Tawil syndrome

• Arrhythmogenic cardiomyopathy (including ARVC)

• Atrial fibrillation (familial forms)

• Brugada syndrome

• Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

• Dilated cardiomyopathy (familial)

• Emery-Dreifuss muscular dystrophy (EDMD)

• Hypertrophic cardiomyopathy

• Jervell and Lange-Nielsen syndrome (JLNS)

• Left ventricular noncompaction cardiomyopathy

• Long QT syndrome (LQTS)

• Naxos disease

• Peripartum cardiomyopathy

• Short QT syndrome (SQTS)

• Sudden cardiac arrest (inherited predisposition)

• Timothy syndrome

• Familial hypercholesterolemia

• Familial amyloidosis